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Pain Relief
Designated Class 2 โ€” Use with special caution
Drug Type

Combination analgesic and antipyretic (ibuprofen + acetaminophen + allylisopropylacetylurea + caffeine)

Form

Tablets

Indication

Relief of headache, shoulder stiffness pain, menstrual pain, back pain, joint pain, neuralgia, muscle pain, sore throat, toothache, post-extraction pain, bruising pain, sprain pain, fracture pain, traumatic pain, and earache; and reduction of fever and chills

Active Ingredients (per 2 tablets)

โ€ข Ibuprofen 130mg โ€ข Acetaminophen 130mg โ€ข Anhydrous caffeine 80mg โ€ข Allylisopropylacetylurea 60mg โ€ข Dehydrated aluminum hydroxide gel 70mg

Inactive Ingredients

Cellulose, hydroxypropylcellulose, lactic acid, D-mannitol, potassium dihydrogenphosphate, silicon dioxide, magnesium stearate, polyvinyl alcohol (partially saponified), talc, titanium oxide, glycerol fatty acid ester, sodium lauryl sulfate

Instructions for Use

  • โœ“Take with lukewarm or cold water. Avoid taking on an empty stomach. Allow at least 4 hours between doses.
Age Dose per use Times per day
Adults (15 years and older) 2 tablets Up to 3 times daily
Under 15 years Do not use โ€”
  • โœ•Do not take if you have had an allergic reaction to this product or any of its ingredients.
  • โœ•Do not take if you have experienced an asthma attack triggered by this product, other analgesics or antipyretics, or cold medicines.
  • โœ•Do not take if you are under 15 years of age.
  • โœ•Do not take if you are pregnant and expecting to give birth within 12 weeks.
  • โœ•Do not use with other analgesics/antipyretics, cold medicines, sedatives, or motion sickness medications.
  • โœ•Do not operate vehicles or machinery after taking this medication (drowsiness may occur).
  • โœ•Do not drink alcohol before or after taking this medication.
  • โœ•Do not take for an extended period.
  • โœ“If any of the following occur after taking, stop immediately and consult a physician, dentist, pharmacist, or registered salesperson: skin rash, redness, itchiness, or bruising; nausea, vomiting, loss of appetite, stomach discomfort, stomach pain, oral inflammation, heartburn, heaviness in the stomach, gastrointestinal bleeding, abdominal pain, diarrhea, or bloody stool; dizziness; heart palpitations; shortness of breath; or blurred vision, ringing in the ears, swelling, nosebleed, bleeding from the gums, bleeding that does not stop, back pain, excessive drop in body temperature, or lethargy.
  • โœ“If constipation or drowsiness persists or worsens after taking, stop use and consult a physician, pharmacist, or registered salesperson.
  • โœ“Seek immediate medical attention if you experience itchy skin, hives, hoarseness, sneezing, itchy throat, difficulty breathing, heart palpitations, or feeling faint (possible anaphylactic shock); severe fever, bloodshot eyes, eye mucus, lip sores, sore throat, widespread rash or skin redness, small pustules on reddened skin, overall lethargy, or loss of appetite (possible Stevens-Johnson syndrome, toxic epidermal necrolysis, or acute generalized exanthematous pustulosis); widespread skin redness, systemic rash, fever, lethargy, or swelling of lymph nodes in the neck, armpits, or groin (possible drug-induced hypersensitivity syndrome); fever, itchiness, rash, jaundice, brown urine, overall lethargy, or loss of appetite (possible liver damage); fever, rash, reduced urine output, swelling all over the body, overall lethargy, joint pain, or diarrhea (possible kidney disorder); severe headache with neck stiffness, fever, or nausea and vomiting (possible aseptic meningitis); pressure-like chest pain, shortness of breath, or cold sweat (possible myocardial infarction); sudden decreased or loss of consciousness, weakness moving one side of the body, headache, vomiting, dizziness, or difficulty speaking (possible cerebrovascular disorder); shortness of breath after mild exertion, dry coughing, or fever (possible interstitial pneumonia); wheezing or difficulty breathing (possible asthma); bruising, nosebleed, bleeding from the gums, fever, pale skin or mucous membranes, fatigue, heart palpitations, shortness of breath, feeling sick and dizziness, or bloody urine (possible aplastic anemia); or sudden onset of fever, chills, or sore throat (possible agranulocytosis).
  • โš Consult a physician, dentist, pharmacist, or registered salesperson before use if you: are currently receiving medical or dental treatment; are pregnant or may be pregnant; are nursing; are elderly; have had an allergic reaction to any drug; have been diagnosed with heart disease, kidney disease, liver disease, systemic lupus erythematosus, or mixed connective tissue disease; or have a history of gastric or duodenal ulcers, ulcerative colitis, or Crohn's disease.
  • โœ“Seek immediate medical attention if any of the following serious symptoms appear:
  • โ€ข Shock (anaphylaxis): Itching of skin, hives, hoarseness, sneezing, itchy throat, difficulty breathing, palpitations, or clouding of consciousness immediately after use.
  • โ€ข Stevens-Johnson syndrome / toxic epidermal necrolysis / acute generalized exanthematous pustulosis: High fever, redness of eyes, eye discharge, sores on lips, sore throat, widespread rash or redness on skin, or small blisters (pustules) on reddened skin that persists or rapidly worsens.
  • โ€ข Liver disorder: Fever, itching, rash, jaundice (yellowing of the skin or whites of the eyes), dark urine, general fatigue, or loss of appetite.
  • โ€ข Drug-induced hypersensitivity syndrome: Widespread reddening of the skin, systemic rash, fever, general fatigue, or swelling of lymph nodes (neck, armpits, or groin).
  • โ€ข Asthma: Wheezing or whistling breath sounds, or difficulty breathing.
  • โ€ข Interstitial pneumonia: Shortness of breath with climbing stairs or slight exertion, dry cough, or fever that appears suddenly or persists.
  • โ€ข Kidney disorder: Fever, rash, decreased urine output, swelling throughout the body, general fatigue, joint pain, or diarrhea.
  • โ€ข Aseptic meningitis: Severe headache with stiff neck, fever, nausea, or vomiting. (More common in people with systemic lupus erythematosus or mixed connective tissue disease.)
  • โ€ข Aplastic anemia: Bruising, nosebleed, bleeding gums, fever, pale skin or mucous membranes, fatigue, palpitations, shortness of breath, feeling faint, or blood in urine.
  • โ€ข Agranulocytosis: Sudden high fever, chills, or sore throat.
  • โ€ข Myocardial infarction: Squeezing chest pain, difficulty breathing, or cold sweat.
  • โ€ข Cerebrovascular disorder: Sudden onset of decreased or loss of consciousness, difficulty moving one side of the body, headache, vomiting, dizziness, slurred speech, or difficulty finding words.
  • โœ“Strictly follow the prescribed dosage.
  • โœ“When removing the tablet from the PTP sheet, press the convex side firmly to break the foil on the back. Do not swallow the PTP sheet.
  • โœ“If symptoms do not improve after 5 to 6 doses, stop use and consult a physician, dentist, pharmacist, or registered salesperson.

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For informational purposes only. Always consult a doctor or pharmacist before taking any medication.